Codeine Base [D.D]

Codeine Base [D.D] Brand names, Codeine Base [D.D] Analogs

Codeine Base [D.D] Brand Names Mixture

No information avaliable

Codeine Base [D.D] Chemical_Formula

C₁₈H₂₁NO₃

Codeine Base [D.D] RX_link

http://www.rxlist.com/cgi/generic/codphos.htm

Codeine Base [D.D] fda sheet

Codeine Base [D.D] msds (material safety sheet)

Codeine_Base_[D.D] MSDS

Codeine Base [D.D] Synthesis Reference

Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)

Codeine Base [D.D] Molecular Weight

299.364 g/mol

Codeine Base [D.D] Melting Point

154 - 156 ^oC

Codeine Base [D.D] H₂O Solubility

<0.1 g/100 mL

Codeine Base [D.D] State

solid

Codeine Base [D.D] LogP

1.809

Codeine Base [D.D] Dosage Forms

Oral solution; Tablet

Codeine Base [D.D] Indication

For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.

Codeine Base [D.D] Pharmacology

Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.

Codeine Base [D.D] Absorption

well absorbed

Codeine Base [D.D] side effects and Toxicity

Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue

Codeine Base [D.D] Patient Information

Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics, phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.

Codeine Base [D.D] Organisms Affected

Humans and other mammals